【摘要】 <正> 我们曾报导溴化α-噻吩甲酰基代甲基三苯鉀与芳胺反应,生成一系列2-(α-噻吩基)吲哚和苯骈吲哚化合物。为考查杂环基团引入对胂叶立德活性的影响;制备了溴化α-呋喃甲酰基代甲基三苯鉮,与芳胺反应得到了像α-噻吩甲酰基代甲基三苯鉮与芳胺反应产物非常类似的结果。为这类化合物的合成提供了又一新的途径。其反应式如下:更多还原

【Abstract】 Reaction of 2-Furanylacylmethyltriphenylarsonium bromide (1) with excess substituted anilines and 1 (or 2)-naphthylamine in N,N-dimethylaniline gave correpon-ding 2-(α-Furanyl)-indoles(2a-d) and 2-(α-Furanyl) benzidole derivatives (3 snd 4). α-Furanylacylmethyltriphenylarsine reacted with substituted benzaldehyds to form corresponding olefin derivatives in high yield. The structures of the products were determined by elemental analysis, colour test, IR and 1H NMR.更多还原