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福建省444例恶性淋巴瘤病理分析

A pathological analysis of 444 cases of malignant Iymphomas in Fujian province

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【作者】 翁景萱黄瑞霞唐瑞文沈云英

【Author】 Weng Jingxuan Dep of pathology

【机构】 福建医学院病理解剖学教研室福建医学院病理解剖学教研室

【摘要】 <正> 近十几年来随着免疫学的研究进展,使恶性淋巴瘤的病理分类进入到一个新的研究阶段。许多学者应用免疫学和细胞生物学方法对各型淋巴细胞的发育、分化以及其相应的形态特征进行了细致的研究和观察,并认为恶性淋巴瘤的发生是停顿在某一个发育阶段的淋巴细胞的异常增生。就此对恶性淋巴瘤提出了新的病理形态分类标准。我们综合参考北京、上海等单位所提出的分类意见,对福建省各地区、市、县的恶性淋巴瘤作十年

【Abstract】 Pathologic analysis of 444 cases of malignant lymyhomas were collected from various different areas in Fujian. pathogic classification was primarily based on classification on proposed by Beijing and Shanghai Lymphoma Sympo- sium 1982--1985. Among there were 202 cases (45. 5% )of Hodgkin’s Lymphoma (HD), 242 cases (54. 5%) of Non-Hodgkin’s Lynphoma (NHL). according to the immunomorphologic classification for B and T cell lymphomas were made respectively 64% and 32%. In 242 cases of NHL, mixed cleaved cell type, lymphoblastie type were most commonly subtypes, followed by non-cleaved cell type, pleomorphous cell type respectively for B and T cell lymphoma. Lymphadenopathy as initial involvemend occurred most freguently (92%), which may be more than one half of these cases developed as systemic nodes involved, but only 8% of the primary tumor were extranodally. From this paper, our cases of T cell Lymphoma had a relatively high frequency (32%), that as other areas on the east coast in our country, The relationships between the geographical distributions of T cell Lymphoma and environmental carcinogenic agents will further research.

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