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鼻腔鼻窦内翻性乳头状瘤超微病理研究

Ultrastructural investigation of inverted papilloma of nasal cavity and paranasal sinuses

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【摘要】 本文报告鼻腔鼻窦乳头状瘤电镜观察。在肿瘤细胞特别是基底细胞中可见有不同时期的核分裂相,胞浆中有线粒体、粗面内质网、丰富的游离核糖体、溶酶体和成束的张力原纤维。通过对上皮—基质交界面的详细电镜观察,更发现基底细胞胞浆成伪足状向基质突出,并围以基底膜。光镜下基底膜均示完整,但在电镜下可见基底膜结构模糊、发育不良甚至中断,这可认为肿瘤细胞在适当条件下,侵袭穿过有病变的基底膜进入基质,从而引起临床的复发和癌变。

【Abstract】 4 cases of inverted papilloma of the nasal cavity and paranasal sinuses were examined with the electron microscope. Special attention was paid to the epithelial-stromal interface. In the papilloma cells mitosis figures in different stages were frequently observed, especially in the basal cells. Those tumor cells contained mitochondria, rough surfaced endoplasmic reticulum and abundant free ribosomes, lysosomes and numerous bundles of tonofilaments. The papilloma cells were clearly demarcated from the stromal tissue by the basement membrane.

  • 【文献出处】 北京医学 ,Beijing Medical Journal , 编辑部邮箱 ,1986年05期
  • 【被引频次】2
  • 【下载频次】25
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