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甲状腺机能亢进症患者血清β2微球蛋白的测定
THE CLINICAL SIGNIFICANCE OF SERUM BETA 2 MICROGLOBULIN DETERMINATION IN BOTH NORMAL PERSONS AND PATIENTS WITH HYPERTHYROIDISM
【摘要】 本文对40名正常人及60名甲状腺机能亢进症患者血清β2微球蛋白进行了测定.结果表明:甲状腺机能亢进患者血清β2微球蛋白水平明显高于正常人(P<0.001),其阳性率为70%.用抗甲状腺药物治疗后β2微球蛋白水平以及阳性率下降,治疗组阳性率为7.5%.未治组与治疗组对比有显著的统计学意义(P<0.01).因此,血清β2微球蛋白可以作为治疗弥漫性甲状腺肿并甲状腺机能亢进症的一个参考指标.
【Abstract】 Serum ■2 microglobulin levels were determined in 60 cases of hyperthyroidism divided into non-treatment and treatment groups. The corresponding measurements were carried out in 20 normal persons as controls. The results showed that serum β2 microglobulin levels were bigher than normal in cases of hyperthyroidism (P<0.001). The positive rate was 70%. When hyperthyroidism had been controlled by antithyroid drugs, the β2 microglobulin levels decreased, and its positive rate fell to 7.5%.The difference between the non-treatment and treatment groups was statistically significant (P<0.01).The serum β2 microglobulin level may therefore be used as a parameter of disease control in diffuse goiter with hyperthyroidism(Graves’ disease) .
【Key words】 Beta 2 microglobulin; Exophthalmic goiter; Hyperthyroidism; Radioimmunoassay;
- 【文献出处】 青岛医学院学报 , 编辑部邮箱 ,1986年04期
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