【摘要】 本实验以手术方法造成146只未成年的LACA小鼠第十二尾椎实验性骨折,以组织学改变的情况评价了不同环境温度和"接骨Ⅱ号"对骨折修复的影响以及肥大细胞与骨痂形成的关系.结果表明:选择小鼠尾椎为骨折部位建立动物模型有许多优点,环境温度为33℃时骨折愈合明显比8～14.5℃时快,但"接骨Ⅱ号"无明显的加快骨折愈合的作用,肥大细胞参于了骨痂的形成.更多还原

【Abstract】 The experimental fractures of the twelfth tail vertebrae of 146 young LACA mice were performed surgically. The effects of environmental temperature and the traditional drug "Fracture Healing No.2" on the healing o these fractures were observed and assessed using the histological changes of the healing fractures as the criteria. The relation between callus formation and mast cells were also noticed. The results showed that: The tail vertebrae of mice could be utilzed as a site for experimental fracture due to several advantages. Fractures in animals kept at 33 degrees Celsius healed more rapidly than those kept at 8～14.5 degrees Celsius. Fractures in animals given "Fracture Healing No.2" did not heal more rapidly than those of the control group. The mast cells took part in the callus formation.更多还原