【摘要】 本文收集我院1971年住院放疗鼻咽癌796例进行分析,讨论影响鼻咽癌预后的有关因素。年轻者预后较好,随年龄的增长,逐渐变差;病理分型的五年生存率以泡状核细胞癌高于低分化鳞癌;临床分期Ⅰ期的五年生存率最好,以Ⅰ至Ⅳ期逐渐下降;临床分型上行型与下行型五年生存率无差异,但上下行型最差;原发灶局限于鼻咽腔的五年生存率较好,超出鼻咽腔越广泛者越差;单侧颈淋巴结转移者预后优于双侧者;颈淋巴结转移N₁、N₂和N₃的五年生存率依次降低;肿瘤放射剂量以鼻咽5000—7000rad、颈淋巴结转移以4000—6000rad较好。更多还原

【Abstract】 An analysis has been made to evaluate the factors affecting the prognosis of 796 patients with nasopharyngeal carcinoma (NPC), treated in 1971. Better prognoses have been found in young patients and they were getting poorer with the increase of age. The 5-year survival rate in this series depended to some extent on the histo-pathologic type of the tumor, showing a higher survival rate for patients with vesicular-nuclear cell carcinoma than those with poorly differentiated squamous cell carcinoma. Gradual decrease of 5-year survival rate was seen from stage I to stage IV; the prognosis of patients with ascending (A) or descending (D) type of advanced NPC showed no significant difference, but a poor prognosis presented in patients with mixed (AD) type NPC. The 5-year survival rate was higher in patients with the tumor limited in nasopharynx (NP) cavity (T1 + T2), but lower in those with tumor exceeded the NP cavity (T3+T4). Concerning the metastasis, the 5-year survival rate of patients with unilateral cervical lymph node involvement was higher than that with bilateral involvement, and was decreasing in order of N1、 N2 and N3 stages. As for radiotherapy, 5000-7000 rad to the tumor in nasopharynx and 3500-5500 rad to the cervical lymph nodes was the optimal dose.更多还原