经额开颅及经鼻显微手术治疗垂体腺瘤的比较

【摘要】 自1958年到1983年,共手术治疗垂体腺瘤262例,其中经开颅手术切除肿瘤150例,经鼻显微手术112例。近5年开展经鼻垂体显微手术后,平均每年收治病人较前20年增加6.7倍。垂体内分泌激素的各种测定检查,是垂体肿瘤早期诊断的重要手段,可使病人的确诊和治疗大为提前。经鼻显微手术对鞍内垂体微腺瘤的85％可作到全部或次全切除(53％及32％),从而减少了术后放疗和复发率,提高了垂体内分泌功能恢复的水平。更多还原

【Abstract】 This paper presents surgical removal of 262 pituitary adenomas in 25 years time (1958—1983). There are 150 cases treated by transfrontal craniotomy and 112 cases by transsphenoidal microsurgical removal. Since 1979 transsphenoidal microsurgical removal of pituitary adenoma has been started in our hospital, patients of pituitary adenoma have increased markedly (6.7 times per year than 20 years ago). According to radiolmmunological assay and several active determination of pituitary hormones, early diagnosis of pituitary adenomas has been established early. The age of the patient has become younger and the time the patient go to the doctor earlier. Transsphenoidal operation may remove intrasellar adeaomas totally or subtotally in 85% of the patients. Postoperative radiation of patients was reduced. Normalization of endocrine function was promoted.更多还原