【摘要】 本文采用~3H-TNT标记化合物,通过离体皮肤实验模型,研究皮肤性状对TNT经皮肤渗透性的影响。结果表明,动物种属及皮肤部位均可影响TNT经皮肤的渗透作用;化学或机械的皮肤损伤均明显增加TNT的经皮渗透量和渗透速度。因此,在生产和使用TNT时,应教育工人保护皮肤,不宜使用有机溶刺洗手。更多还原

【Abstract】 The influence of skin properties on the percurtaneous permeability of TNT have been studied using radioactive labelled ~3H-TNT in vitro skin model. The results showed that the percutaneous permeability of TNT can be effected by the animal species and different part of skin, The penetration of TNT through the injured skin was much easier compared with the intact skin. Therefore, workers should be educated not to use organic solent as skin cleaner.更多还原