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高温作用下机体某些生化指标的探讨

The Influence of Exposure to High Ambient Temperature on the Biochemical Responses

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【摘要】 本实验研究了气温35℃作用下大鼠某些生化指标的变化。从大鼠每天受热两小时,连续23天的实验结果可看出,大鼠受热第1和第15天肛温和出汗量增高的同时,下丘脑组织中cAMP、血清GPT和LDH5水平明显提高(P<0.01),而心脏脏器系数则于实验的第17天、生长率于实验结束时始观察到明显低于未受热组(P<0.05)。

【Abstract】 Biochemical parameters in healthy adult male rats exposed to an ambient temperature of 35℃ 2 hours a day for 23 days have been monitored and compared with those of normal unexposed rats. The results showed that, with the rectal temperature arid perspiration increasing the levels of cAMP in hypothalamus tissue, and GPT and LDH5 in serum were found significantly increased(P<0.05). The organic-content of the heart was also higher in the exposed group (P<0.05) on the 17th day of exposure. Growth rate of the animals exposed to hot environments significantly reduced (P<0.05)at the end of the experiment. All the exposed rats did not show heat disorders in the entire experimental period. It is clear from the above results that the early biochemical responses to heat stress may serve as the parameters available for monitoring the healthy workers exposed to hot environments and provide a scientific basis for the formulation of hygienic standards.

  • 【文献出处】 中华劳动卫生职业病杂志 ,Chinese Journal of Industrial Hygiene and Occupational Diseases , 编辑部邮箱 ,1985年03期
  • 【被引频次】12
  • 【下载频次】17
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