【摘要】 <正> 据报道,手针家兔或电针大鼠,痛阈明显升高的同时,纹状体和下丘脑内甲-脑啡肽和亮-脑啡肽含量明显增加;电针也能使大鼠纹状体释放亮-脑啡肽和提高猴侧脑室脑脊液亮-脑啡肽的含量。许多实验还证明了γ-氨基丁酸(GABA)和乙酰胆碱(Ach)不同程度参与针刺镇痛过程。为探讨针刺过程中脑内亮-脑啡肽与 GABA或 Ach 系统的功能是否存在一定关系,我们分更多还原

【Abstract】 Electroacupuncture produced a significant incr-ease of the leucine-enkephalin level in the rat stria-tum.The increase of leueine-enkephalin was abolis-hed by pre-injuction(i.p.)of bicuculline,a blo-cker of GABAergic receptor,or atropine,a blockerof muscarinic cholinergic receptor;But,after theinjuction of bicuculline the leueine-enkephalin con-tent in the oblongata plus pons was elevated by theelectroacupuncture.The results indicate that the ch-anges of leucine-enkephalin concentration in ratbrain induced by electroacupuncture were associatedwith the functions of GABAergic receptor or musca-rinic cholinergie receptor.更多还原