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国产碘伏消毒效果的初步研究

PRELIMINARY STUDY ON GERMICIDAL EFFECT OF CHINA-MADE IODOPHOR

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【作者】 严胜张果韩常生夏立人乔国荣

【Author】 Yan Sheng Zhang Guo~* Han Changsheng~(**) Director: Xia Liren Qiao Guorong (Shanghai Hygiene and Anti-epidemic Center) * Anti-epidemic Station of H(?)angpu District of Shanghai. ** Anti-epidemic Station of Luwan District of Shanghai.

【机构】 上海市卫生防疫站上海市黄浦区卫生防疫站上海市芦湾区卫生防疫站上海市卫生防疫站

【摘要】 <正> 碘伏是碘与表面活性剂相络合的产物,表面活性剂作为载体增加了碘的溶解度。由于碘伏中的碘在表面活性剂中缓慢释出,故其杀菌作用较持久,刺激性低,着色作用基本消失。国外现将之广泛用于外科器械、手与食具等的消毒,国内尚未见有同类产

【Abstract】 The germicidal effect of China-made iodophor was determined in laboratory. The results indicated that the bactericidal action of China-made iodo phor was similar to that of Japan-made iodophor (Isodine) and better than that of tincture iodine and bromogeramine. A solution yielding 10 ppm available iodine killed 99.9999% of Escherichia coli, Staphylococcus aureus and pseudomonas aeruginosa after 2 min of action; 50 ppm killed these bacteria completely after 8 min of action. When the concentration increased to 150 ppm, the spores of Bacillus cereus could be killed completely after 90 min, 200 ppm could kill spores of B subtitis var. niger and destroy HBsAg after 120 min and 30 min respectively. The bacterieidal efficacy of iodophor would decrease in presence of organic substances. The undiluted Chinamade iodophor was quite stable, while the vailable iodine in diluted solution dropped rapidly by 54.9% after 2 days and by 91.5% after 7 days.It is recommended on basis of experimental results that 150 ppm with a 30 min dwelling time can be used for routine disinfection of environment and 200 ppm with a 120 min dwelling time is required for sterilization of surgical instruments and disinfection of articles contaminated by hepatitis B patient.

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