【摘要】 <正> 白肌病(White muscle disease)为硒与维生素 E(Se—E)缺乏性综合症,系多种家畜、家禽的一种地方性营养性代谢病。动物的 Se—E 缺乏因子,所作用部位和引起的症状,随动物种属不同而有明显差异。家畜,主要累及骨骼肌、心肌和肝脏,家禽则表现为渗出性素质。该病病理组织学观察已有许多报告,但超微结构研究很少。犊牛白肌病心肌的电镜研究,迄今尚未见报导。作者发现犊牛白肌病以心脏损害为主,在许多方面类似克山病,对探讨克山病发病学或病因学颇值借更多还原

【Abstract】 Through macroscopic and microscopic and electron-microscopic studies,we have observed 2 cases of white muscle disease of calves and made analy-sis of its pathology and ultrastructural pathology.The chief damage is inthe heart,while changes in the skeletal muscles and othet organs are mild.Thete ate scattered necrotic foci in the heart,especially prominent on theinner and outer layer of the left ventrieular wall.The pathological changesin the myocardial cells are calcification of the mitochondrtia,band-like disintegtation of the myofibtils,and non-specific damage to the satcolemma.The above changes are a kind of coagulative myocotolysis.The chetactetis-tic of these pathological changes is similat to that of acute Ke-shan disease,characterized by necrotic catdiomyopathy.This (?)white muscle diseased calvemay be used as a naturtal model fot the study of Keshan Bisease.The alteration of the myocatdial cell originates from the damageto the sarcolemma.This may result from loss of control over theperoxidation of the cell membrane beeause of selenium deficiency.更多还原