【摘要】 <正> 自从1974年至1977年在四川省冕宁县四个公社的观察结果表明用补充亚硒酸钠的方法预防急型及亚急型克山病有明显效果以来,硒缺乏与克山病发病之间的关系引起许多人的兴趣,但人们关心长期补充硒使急型和亚急型的病人减少了,是否自然慢型克山病的病人会更多还原

【Abstract】 A ten-year and a seven-yearintervention study has been carriedout in Mianning county Sichuan p-rovince,and its neighbour,Xidecounty by using selenium tabletsor selenium fortified salt as sele-nium supplement.The presence ofabnormal changes on ECG and he-art roentgenograph but no clinicalsymptoms were adopted as diagn-ostic criteria of latent type of Ke-shan disease.Because some ofchanges in ECG,such as rightbundle branch block and heart enl-argement would be stayed for life--long,surveys were conductedonly in children after seleniumintervention in treated group andin children in non-treated group atthe same age.The results showed that the nu-mber of latent type of patients inselenium treated group was lessthan that in non-treated group si-gnificantly (X~2=5.80 0.01<P<0.025) and the incidence of abn-ormal changes in ECG and he-art roentgenograph was less in tr-eated group too.It is suggested from this surveythat selenium,which is effeetivein lowering incidence rate of acute and subacutc type of Keshan disea-se,incapable of preventing theheart from slight changes,as sh-own by ECG and heart roentgeno-graph,but the occurrence of heartdamage in selenium supplementedgroup is decreased.Therefore,selenium might be one of the fact-ors in the etiology of Keshan dis-ease.更多还原