【摘要】 <正> 多相分散系药物制剂,尤其是多相分散系注射剂如:多相脂质体混悬型静脉注射剂、静脉乳剂等,已应用于临床,在许多治疗领域中显示了剂型的优越性,因此控制该剂型质量及其物理稳定性和粒径限度等成为国内外目前正在深入研究的重要课题。国外文献报道了用荧光标记法,由荧光—温度陡变测定脂质体相转变(phase transition)温度,发现与其更多还原

【Abstract】 In this report, a new method is presented for measuring the stability of polyphase liposome dispersion as intravenous injection in the form of suspension. From conductivity-temperature curve of the dispersion the temperature of phase transition may be infered. It is relative to the stability of the dispersion. The result of the method agreed with that of subsidence analysis, data of size distribution.更多还原