【摘要】 <正> 二氟一氯甲烷(F₂₂)经高温裂解制备四氟乙烯时所产生的残液,不仅组份极为复杂,而且毒性亦较大。动物或人一次吸入高浓度残液气可引起严重的急性肺损伤、纤维化,甚至死亡。本文叙述用¹31Ⅰ标记人血清聚合白蛋白更多还原

【Abstract】 The toxic effects of a mixture of fluorocarbon gas evoled from the waste discharge during the cracking process of chlorodifluoromethane(F22) on the lungs of rabbits have been investigated. The sixteen rabbits were divided into two groups: acute and subgas for one hour with a concentration of 2500～3000ppm as acute inhalation group. Six rabbits we reexposed to the fluorocarbon gas for one hour with a concentration of 400 ppm for six days as subacute inhalation group. At 12th hour after acute exposure, pulmonary isotope scanning showed significant damage of lung tissue. The lung was markedly enlarged and radioactive distribution was uneven. These changes suggested that pulmonary blood flow was disturbed and capillary was damaged. But X-ray examination did not show any change in the chest. In addition, there was a defect area of rabioactivity in the middle lobe of the right lung in a rabbit, Which suggested the site of embolism of pulmonary blood vessel. In the other group of subacute inhalation, pulmonary isotope scanning. The results indicated order to obtain a valid pulmonary toxicity of the mixture of fluorocarbon gas in rabbits, it is necessary to use a pulmonary isotope scanning technique. The results showed that the pulmonary toxicity of fluorocarbon gas in rabbits maymainly be pulmonary capillaries damage.更多还原