【摘要】 <正> 在地方性氟中毒流行区(简称地氟区),较准确地查明氟骨症患病率较难。如把临床所见的骨症状及/或骨关节畸形,作为诊断氟骨症的指标,则有可能把强直性脊柱炎,骨更多还原

【Abstract】 Three hundred nineteen inhabitants in three endemic fluorotic villages had beensurveyed.The fluoride concentrations of drinking well-water were 3.04～5.90 ppm.Those patients who suffered from early stage of osteofluorotic changes mighthave no abnormal manifestations in X-ray films of their bones,but yet their serumand/or urine fluoride,serum alkaline phosphatase activity and urine hydroxyprolinewere elevated.Some of them had biochemical disturbances which were in keepingwith hyperparathyroidism.We suggested that,in an endemic fluorotic region,the above mentioned biochemi-cal parameters might be used as supplementary indications for the early diagnosis ofendemic osteofluorosis,if rickets,osteomalacia,renal osteodystrophy and variousother bone diseases had been ruled out.更多还原