【摘要】 <正> 病毒性肝炎是威胁人类健康的世界性传染病。乙型肝炎表面抗原(HBsAg)无症状携带者分布广泛,据世界卫生组织(WHO)报道全世界约有2亿多人。我国人群 HBsAg更多还原

【Abstract】 An investigation was conducted in 589 pupils of the Hexi District in Tianjin forHBV infection.A total of 180 pupils are found to be infected or had been infectedbefore.The incidence of HBV infection was 30.56%.HBsAg positive rate was 3.90%(ELISA),anti-HBs positive rate 12.73% (SPRIA) and anti-HBc positive rate 24.96%(ELISA).Among the HBsAg positive pupils,HBeAg and anti-HBe positive rate were47.8% and 13.04% respectively.The degree of blood infectivity could be inferred fromthe presence of HBV infection in sera examined.In our series 12.8% patients wereinfectious.Family aggregation analysis showed that the clustering distribution of HBsAgpositives in family is extremly significant (X~2=21.21, P<0.005).The relative risk offamily aggregation for families with positive index is ten times higher than that ofthe negative families.Mothers who are HBV carrieres in family are important soucesof family infection (P=0.031<0.05).It is believed that family aggregation results fromhorizontal and vertical transmission.Therefore,the major measures for decreasingfamily aggregation and controlling HBV infection are protection of pre-school chil-dren against family horizontal transmission and blocking vertical transmission frommother to infant.更多还原