【摘要】 按不同实验条件制备五组供样动物组织浸液,用放免法测定其受试组血浆皮质酮含量,观察各供样组组织浸液活性。结果提示:①组织浸液活性于注射后半小时达最高峰,至少可维持2小时;②无论在正常条件下或在付肾切除条件下,注射ACTH均可抑制组织浸液活性。推测组织浸液活性因子可能是一种天然存在的生理性物质。更多还原

【Abstract】 Under different experimental conditions male rats regarded as donors are divided into 5 groups,Level of recipient plasm corticosterone of rats determined by RIA is used as an index for assay of tissue extracts activity from donors.The result shows (I) tissue extract activity reached the highest at 30 minutes after injection and last for 2 hours at least (2),it was also observed that ACTH has anegative feedback effect on tissue extract activity either in physiological or in adrenalectomized donors perhaps the factor found in tissue extract might be a kind of physiological material similar to tissue CRF.更多还原