【摘要】 用钠-钾合金代替金属锂分解三间甲苯膦生成（3-CH₃C₆H₄）₂PK,后者与二磺酸酯（V）反应形成（-）-3-CH₃-DIOP,粗产品经用醇、醚处理得到（-）-3-CH₃-DJOP,产率为78%。Rh（I）-（-）-3-CH₃-DIOP催化剂对Ia和Ic的氢化具有较高的立体选择性,旋光产率分别为91和92%。对Ib和Id的氢化仅有中等的立体选择性,旋光产率分别为80%和70%。更多还原

【Abstract】 Tris（3-methylphenyl）phosphine was cleaved with sodium-potassium alloy in place of metallic lithium to give （3-CH₃C₆H₄）₂PK which reacts with ditosylate（Ⅴ） to form （-）-3-CH₃-DIOP. The treatment of the crude product with alcohol and ether （-）-3-CH₃-DIOP is obtained in 78% yield.Rh（Ⅰ）-（-）-3-CH₃-DIOP catalyst possesses a higher stereoselectivity for the hydrogenation of Ia and Ic, and the optical yield is 91 and 92 per cent, respectively, for the hydrogenation of Ib and Id possesses only a moderate steroselectivity, and the optical yield is 80 and 70 per cent respectively.更多还原