【摘要】 CL-1500能使 CCl₄对小鼠的 LD₅₀增大。大鼠静注 CL-1500 100mg/kg,可使胆汁流量增加50%;大鼠灌胃100mg/kg 能明显抑制 CCl₄所致的谷—丙转氨酶的升高。CL-1500小鼠静注 LD₅₀为729.5±2.9mg/kg,皮下注射为1732±176mg/kg。更多还原

【Abstract】 1.CL-1500 increased the LD₅₀ of CCl₄. 2.CL-1500（100mg/kg,iv）caused a significant increase of bile flow in rats. 3.The rise of serum transaminase was observed by the administration of CCl₄.This transaminase rising action of CCl₄ was inhibited by the administration of CL-1500（100mg/kg,po）in rats. 4.CL-1500 LD₅₀ is 1732±176mg/kg（sc）and729±2.9mg/kg（iv）on mice.更多还原