【摘要】 对1979年4月—1984年10月期间7,676例次胃粘膜活检材料中检出的362例轻度以上异型增生的病例进行了观察。到1985年3月止,有随访结果者100例(27.6%),随访时间0.5—5年,平均22个月,随访次数1—6次,平均1.8次/人。100例异型增生的随访结果如下:19例病变减轻,57例保持不变,24例病变加重,其中7例发生癌变,胃手术切除标本经病理证实均属早期胃癌,包括微小胃癌和小胃癌各1例。此外,对异型增生的演变趋势、临床处理原则及胃镜病理活检的意义作了讨论和评价。本研究提示,对胃粘膜异型增生病例进行定期随访,不失为当今胃癌计划防治工作的重要实际手段。更多还原

【Abstract】 The observation of 362 cases of gastric dysplasia (mild or morderate) found in 7,676 gastric biopsies during the period of April 1979 to October 1984 was carried out. Up to March 1985, 100 cases were followed up (27.6%), with the follow-up duration from 0.5 to 5 years (average 22 months) and the frequency of 1 to 6 times (average 1.8 times/person). The results of the 100 cases of gastric dysplasia were as follows: 19 cases improved, 57 unchanged and 24 aggravated. Of the 24 aggravated cases, 7 became cancerous. The pathology of all 7 resected specimens was in the early stage, including 1 case of micro-cancer and 1 case of mini-cancer. Besides, the evolutive tendency of dysplasia, principles in clinical management and significance of endoscopic gastric biopsy were commented and discussed. It is suggested that regular follow-up by endoscopy and biopsy for the dysplastic cases is an important and practical method in the prevention and cure of gastric cancer.更多还原