【摘要】 对历城县142,879名农业人口进行精神发育迟滞流行病学调查,共查出患者378例,患病率为2.65‰。轻、中、重各型分别为68.78％,23.28％和7.94％。分析了本病在农村地区的流行特征,调查了生前、分娩和生后与发病有关的因素,提示本病的发生与环境,遗传等多种因素有关,因此应采取综合性防制措施。更多还原

【Abstract】 In order to find out the epidemic feature and the etiological clue of mental retardation (M. R.) in rural aera of Shandong Province, the prevalence study has been conducted in Licheng County from May 22 to June 41984. According to the topography of Licheng County is divided three types of region, namely mountainous, hilly and flatland, a total number of persons 142, 879 are selected by stratified-clustering sampling for survey. The result of inverstigation indicates that the number of 378 patients are detected, the point prevalence rate is 2.65‰. Three levels of M. R. mild, moderate, severe make uP 68.78%, 23.28%, 7.94%, respectively. The rank of prevalence rate by topography is mountainous (Xiying District), hilly (Shaoer D.), flatland(Dongjia D.), i. e. 4.16‰, 2.85‰, 1.62‰. There is a difference between male and female in prevalence rate, sex ratio being 1.4:1. The prevalence is decreasing with the increase of age, but a remarkable peak appears in 30-49 age group in Xiying District. The etiological factors have been primarily surveyed, prenatal factors are mainly responsible for the formation. 31.45 percent of patient have family history, among them two thirds attribute to first-degree relative, meanwhile the number of cases who have family history in the group with etiological factor is larger than that in another one without etiological factor. Furthermore, the prevalence of M. R. from Patients’ children is 11.65%, a rate much higher than that in general population.更多还原