【摘要】 小鼠经注射自制抗T细胞血清后次日的T细胞数和百分率显著下降(P<0.001),以此建立T细胞减少动物模型。小鼠连续使用除毒河豚肝油(0.05ml/鼠/天,S.C.共5天)能使T细胞百分率与药前比下降不明显(P>0.05),而对照组显著(P<0.001);用药8天停药4天的血清血凝素抗体滴度和脾细胞溶血空斑数较对比组高(P<0.001,P<0.02)。表明该药对此模型具有一定免疫增强作用。更多还原

【Abstract】 The percentage and number of T-lymphocyte in mice were significantly decreased(p<0.001) the day after anti-lymphocyte serum (0.2ml/mouse i.p.) was injected.The percentage of T-lymphocyte in mice decreased less remarkably (P>0.05)after administration of Fugu Liver Oil without TTX (0.05ml/mouse s.c., once daily for 5 days) than that before the experiment, whereas it decreased significantly(p<0.001)in control group.The hemagglutinin titer and plaque forming cell increased on the 5 th day after the last injection which lasted for 8 days.The results suggest that Fugu Liver Oil without TTX has immunopotentiation in mice pretreated with antilymphocyte serum.更多还原