【摘要】 1980年1月至1983年10月对甲亢性心脏病连续性19例患者应用甲状腺次全切除术与心得安联合治疗。本组性别女10人、男9人,年龄分布25至55岁。本文描述了临床资料及严格的诊断标准。19例中16例采用β—受体阻滞剂心得安作术前准备,3例采用心得安及卢戈氐液联合准备。主要优点为药物副作用少及术前准备时间缩短(平均4.9天)。全组术后平均追踪2.5年(1.2至4.10年)。术后无甲亢危象及死亡,亦未见甲状腺功能低下及甲亢复发。研究证明本疗法为甲心病的一种疗效迅速、安全和有效的治疗方法。本文对疗法的临床基础以及手术安全保证亦作简要讨论。更多还原

【Abstract】 We employed subtotal thyroidectomy and propranolol for the therapy on 19 consecutive patients with thyroid heart disease from January 1980 to October 1983. There were 9 male and 10 female patients, ranging from 25 to 55 years of age. Their clinical data and the strict criteria of diagnosis were stated. Among these patients, 16 had received propranolol (beta-adrenoreceptor blocking drugs) preoperatively and 3 the treatment of propranolol with Lugol’s solution. The major advantage of these agents in a preoperative preparation is that the incidence of adverse drug reaction is lower and the period of time shortened (average 4.9 days). In this study, the 19 patients were followed up for an average of 2.5 years after surgery, ranging from 1.2 to 4.1 years, with no death and no thyroid crisis postoperatively. There was no hypothyroidism and recurrent hyperthyroidism developed postoperatively. The clinical basis of therapy and the safeguard of surgical procedures were also briefly discussed. Our study has confirmed that this therapy can yield prompt control of thyroid heart disease, and is an effective and safe treatment, too.更多还原