【摘要】 应用微电极技术研究参附注射液的电生理学作用,实验采用两种方法进行,用16只在位兔心室肌细胞和11份离体心肌组织灌流,在静脉注射2ml参附注射液或灌流液中加入5％参附注射液后,动作电位○相最大去极化速率适度地增加,但动作电位高度,动作电位时程和有效不应期未见改变。更多还原

【Abstract】 Microelectrode techniques were used to study the electrophysiological effects of SHENFU injection. 16 rabbits’ ventricular muscle cells in situ and 11 preparations of ventricular muscle perfused with Tyroide’s solution containing 5% SHENFU were studied. After 5-7 minutes, 2 c.c. SHENFU intravenous injection or within 15 minutes of perfusion with 50% SHENFU, the maximum rate of rise of the action potential (Ⅴ max) was moderately increased (P<0.01), but action potential height, action potential durations at 100%, 50% levels of depolarization, effective refractory period and heart rate were not significantly altered.更多还原