【摘要】 <正> 乳酸脱氢酶（LDH）同工酶具有相对的组织特异性。1963年Blanco 和Goldlerg 在人精液中发现了LDHx 同工酶,该酶只存在于生精细胞和精子中,位于LDH₃与LDH₄之更多还原

【Abstract】 Lactate Dehydrogenase Isoenzyme-x（LDHx）is a specific enzyme of spermatozoa andsperm.The“band-x”appeared in a major area of LDH activity between LDH₃ and LDH₄ onLDH electrophoretic pattern.The polyacrylamide gel electrophoresis（PAGE）pattern of the LDHx of adult humansperm from 52 cases of male sterility and 12 cases of gossypol-treated volunteers wasreported.These results revealed:1),In male sterility group,the patients were divided intotwo groups according to the number of spermatozoa/ml spermatic fluid.The average percentageof LDHx activity of two groups showed no significant difference（P>0.05）.But they wereapparently less than that of the normal（42.6%）;2),In gossypol-treated group,the LDHxactivity showed marked decrease（even zero）.The gossypol inhibited the activity of LDHx.A lowering in the relative activity of LDHx or its total absence would certainly reflecta corresponding change in the function of the spermatozoa.更多还原