【摘要】 本实验用HRP逆行性轴浆运输技术,对猫丘脑中央外侧核的传入纤维联系及其局部定位关系进行了观察。投射至丘脑中央外侧核尾侧区的主要核团包括:外侧膝状体腹核背侧带、丘脑网状核特别是它的背侧部、上丘深层,以同侧为主。板内核、丘脑下部外侧区和黑质网状部神经元的轴突终止在同侧丘脑中央外侧核吻侧区。丘脑中央外侧核全长的传入起自脑干网状结构和前庭神经核,呈双侧投射。前者以同侧为主,后者以对侧占优势。同侧未定带,顶盖前区、动眼神经核周围的细胞群、对侧三叉神经感觉主核、楔束核、薄束核以及小脑齿状核内也含有少量标记细胞。我们还观察到HRP注射中心区位于中央外侧核并扩散至丘脑腹前核者,同侧脚内核含大量HRP阳性细胞,而Gudden被盖腹侧核内充满密集的标记终末。这些结果表明,丘脑中央外侧核可能涉及多种感觉和运动功能。更多还原

【Abstract】 The afferent connections and topographical organization of the central lateral nucleus were studied with HRP retrograde tracing technique in 10 adult cats. The central lateral nucleus received projections from the forebrain, brainstem and cerebellum. The nuclei, projected to the caudal region of the central lateral nucleus, included the dorsal division of the ventral lateral geniculate nucleus, the thalamic reticular nucleus and the deep layers of superior colliculus, primarily on the ipsilateral side. The intralaminar thalamic nucleus, the lateral hypothalamus and the reticular part of substantia nigra sent axons to terminate in the rostral region of the central lateral nucleus, with an ipsilateral predominance. The nuclei, projected to the whole length of the central lateral nucleus, were the vestibular neuclei, the reticular formation of brainstem, zona incerta, pretectal area, cells surrounding the occulomotor complex, principal sensory trigeminal, cuneatus, gracilis as well as cerebellar dentate. The vestibular nuclei and the reticular formation of brainstem were found bilateral projection, the former predominantly in contralateral, the latter mainly in ipsilateral part. Except the zona incerta, pretectal area and cells surrounding the occulomotor, the rest were labeled primarily on the contralateral side. If HRP was injected into the central lateral nucleus and spread to the ventral anterior nucleus of thalamus, a lot of HRP-positive cells were found in the entopeduncular nucleus, while the ventral tegmental nucleus of Gudden was filled with densely labeled terminals mainly on the ipsilateral side. These findings indicate that the central lateral nucleus of thalamus may be involved multiple sensory and motor functions.更多还原