【摘要】 <正> 众所周知,人体外周血淋巴细胞的染色体对电离辐射最为敏感,数rad 剂量的照射即可见到人体外周血淋巴细胞染色体畸变率的增加。一些研究表明,染色体畸变率与所受照射剂量有依赖关系,随照射剂量增加而增加。由于电离辐射后染色体畸变出现早,并持续较长时间,且畸变量与照射剂量呈线性关系,故国内外均广泛采用染色体畸变率作为辐射事故的生物剂量仪,以及远期效应的观察指标。计数外周血淋巴细胞染色体的畸变量来估算受照人员的辐射剂量,不仅较为简易,更多还原

【Abstract】 The relationship between chromosome aberrations of human peripheral bloodlymphocytes in vitro and radiation dose was investigated.The whole bloodsamples of 9 healthy adults were irrdiated with various dose（15～100R）of^6（?）Co γ ray and cultured for 52 hrs.by microtechnique.All chromosome typeaberrations were counted and analysed.The results were as follows:（1）According to criteria of WHO,the resulting data were filled to three models,Y=a₁+b₁D,Y=a₂+c₂D²,Y=a₃+b₃D+c₃D³.（2）Their dose response curveswere drawn.The frequency of acentrics was higher than those of dicentrics pluscentric rings at a low dose range of ionizing radiation.更多还原