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线粒体与白血病 Ⅱ.人白血病细胞线粒体超微结构的分析
Mitochondrial Ultrastructure of Human Leukemic Leucocytes
【摘要】 本实验通过电镜和SDS 聚丙烯酰胺凝胶电泳分析了人白血病细胞的线粒体超微结构和蛋白组分,发现白血病细胞的结构出现一定程度的病理损伤,嵴缺少,内膜缺损以及基质出现空泡等;它的蛋白组分也出现了明显的变化。
【Abstract】 The mitochondrial ultrastructure and membranous proteins in human leukemic cells are studied with electron microscope and polyacrylamide SDS gelelectrophoresis.The micrograph showed leukemic mitochondria with the different size,specific structural damage,fewer cristae,vacuolated matrix and varying degrees of awelling.It was also found that the number of the membranousprotein bands of leukemic mitochondria decreased significantly.The structuraldamage of mitochondria cristae and diminution of menbranous proteins maydisturb mitochondrial proteins synthesis or result in abnormality of leukemiccells.
- 【文献出处】 哈尔滨医科大学学报 ,Journal of Harbin Medical University , 编辑部邮箱 ,1985年03期
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