【摘要】 在微波照射成年大鼠睾丸后1天至70天。用光镜和电镜观察促性腺激素细胞。发现该细胞粗面内质网池扩大并含有絮状物和线粒体出现膨胀、嵴断裂和嵴间隙扩大等变化,尤以14天组最为显著。细胞内成熟颗粒百分比大于成熟前颗粒百分比,单位面积内颗粒数目最多,且PAS阳性反应最强。更多还原

【Abstract】 Twenty-five adult male rats(5 rats in eachgroup) were used. After a single irradiation(2450 megacycle, at 40. 5±℃, 15 min), therats in each group were decapitated atdifferent intervals (1, 7, 14 and 70 days). Under the light microscope, we meas-ured in each group one hundred FSH-andLH-cells with Paget’s staining sections.When the average cell diameter and thenucleus diameter and the ratio of cytoplasmto nucleus were compared with the controls,there were no significant statistical differ-ences. We also took count of five hundredFSH-and LH-cells with PAS reaction sec-tions. The results were as follows: whenthe FSH-cells of the experimental groupswere compared with the controls, the mostIntensive PAS reaction of the granules wasobserved in the 7 and 14 days; but as forthe LH-cells, only in 14 days(u value>1. 96.P<0. 01). Under the electron microscope when theaverage granule diameter of FSH- and LH-cells was compared with the controls therewas no significant statistical difference. Bymeans of taking count of granules of boththe cells within 150 und micro squaresrespectively, the maximum mean of theunit square granules was in the FSH-cellsof 1 and 14 days (q value 4. 13,0. 05>P>0. 01). The organelles of gonadotroph cells were more strikingly affected on the RER andmitochondria only. The majority of mito-chondria of the FSH-cells were swollen, andits cristae were broken and the spaces ofcristae were swollen, too; but there were nobroken cristae in the LH-cells. the RER ofthe FSH-cells was more dilated than that ofthe LH-cells, and contained more densecatkiny contents (except 70 days andLH-cells).更多还原