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兔脑水肿模型脑组织放射性定量测定

QUANTITATIVE DETERMINATION OF RADIOACTIVITY IN RABBIT BRAIN EDEMA MODEL

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【作者】 程冠生; 陈国华; 胡全美; 虞佩兰; 沈菊英; 吴中匡; 徐正谷; 杨于嘉; 周佩芳;

【Author】 Cheng Guansheng Chen GohoaRadioisotope Laboratory, Hunan Medical CollegeHu Quaumei Yu Peilan Shen Juying Wu Zhougkuang Xu Zhenggu Yang Yujia Department of pediatrics, The First Affiliated Hospital, Hunan Medical College

【机构】 湖南医学院同位素室; 湖南医学院第一附属医院儿科教研室; 湖南医学院第一附属医院儿科教研室;

【摘要】 在混合性脑水肿动物模型中,于血管内注入放射性标记分子。实验结果表明,脑水肿动物的脑组织中放射性物质含量的增加与水含量的增加有正相关关系。

【Abstract】 Thirty rabbits were randomly divided into experimental and control groups. Typhoid endotoxin brain edema was induced by Yu’s method(1).Both groups had been injected with 0.5μ Ci Hippuran-131I solution following the endotoxin or saline infusion. Radioactivity and water contents of the brain tissue Were determined.Results showed radioactivity in the brain tissue of the experimental group was significantly higher than that of the control, which showed a positive correlation with the increment of water content

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