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小儿肾小球疾病微循环变化观察

Observation on the Changes of Nailfold Microcirculation in Children with Glomerulonephropathy

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【作者】 郭植材; 姚龙; 李贯南;

【Author】 Guo Zhi-cai et al

【机构】 广西医学院儿科; 广西医学院儿科;

【摘要】 从33例急性肾小球肾炎及17例肾病综合征病儿的甲皱微循环作了动态的连续观察发现:①全部病儿的甲皱微循环管袢在单位范围内呈非发夹形者均超过20%;②在灰病急性期,单位范围内微循环管袢数目减少,动脉肢缩短、狭小,部分管袢模糊,此时病儿有高血压、浮肿等体内胺类物质活性亢进的表现,而在疾病恢复期,随着临床症状的好转,微循环亦相应恢复;③2/3以上病儿微循环内发生红细胞聚集,此与病儿血浆内球蛋白的比例失调有明显关系。

【Abstract】 The paper presents a survey of the subungual microcirculation in 74 normalchildren, 33 cases of acute glomerulonephritis and 17 cases of nephrotic syndromerespectively. All inspected were children under 15 years of age. The comparisonof the observed data in these 3 groups indicated that the significant changes ofmicrocirculation during the course of kidney disease were: (1) the microvascularities became slurry in 18.9%,meanwhile the blood-flow slower in 45.5%,the streamlinebecame granular in 84.9% and the venous loops showed tortuous in more than 60%of the cases. (2) the estimation of the capillary loops found a significant reduc-tion in number of visible capillaries and marked shortening and narrowing of thearteriolar loops. All the morphological and hemodynamic changes of microcircul-ation may continue throughout the course of kidney disease, and the microcircul-ation became normal when the disorder was cured.

  • 【文献出处】 广西医学 ,Guangxi Medical Journal , 编辑部邮箱 ,1985年01期
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