节点文献
人参对人血小板聚集性和丙二醛生成的影响
EFFECTS OF GINSENG ON PLATELET AGGREGATION AND THE FORMATION OF MALONDIALDEHYDE(MDA) IN MAN
【摘要】 本文研究了人参对人血小板聚集性和丙二醛生成的作用。观察到12名健康受试者口服人参粉末胶囊(1.5g人参)后,由花生四烯酸、ADP、凝血酶和肾上腺素诱导的血小板聚集?明显抑制,同时由花生四烯酸和凝血酶诱导的血小板丙二醛的生成也受到抑制。结果表明,人参对血小板聚集的抑制作用可能与抑制血小板前列腺素的代谢有关。
【Abstract】 The effects of red ginseng (Panax ginseng C. A. Meyer, root)on platelet aggregation and MDA were investigated ex vivo in 12 healthy sub-jects by an oral administration of 1.5g. The study demonstrated that red ginsenginhibited platelet aggregation induced by arachidonic acid (AA), ADP, throm-bin and epinephrine. It was also observed that red ginseng exhibited the inhibi-tory effect on the formation of human platelet MDA by arachidonic acid andthrombin. It was shown that the inhibitory effects of red ginseng on plateletaggregation might be due to the inhibition of platelet prostaglandin metabolism.
【Key words】 ginseng; platelet aggregation; malondialdehyde (MDA); prostaglandin;
- 【文献出处】 中国临床药理学杂志 ,The Chinese Journal of Clinical Pharmacology , 编辑部邮箱 ,1985年04期
- 【被引频次】10
- 【下载频次】62