【摘要】 本文报道了低剂量⁶⁰Coγ线照射后人外周血淋巴细胞质膜表面受体功能和结构的变化。结果表明,25拉德照射后淋巴细胞活性 E 玫瑰（E_a）花环形成百分率显著减少（p<0.01）,100拉德照射后未见进一步减少;25拉德照射后淋巴细胞小鼠红细胞玫瑰（M_E）花环形成百分率明显下降（p<0.01）,100拉德照射后下降更显著;25拉德照射后淋巴细胞膜表面免疫球蛋白 G 阳性（S_mI_gG⁺）细胞百分率减少,100拉德照射后减少更显著（p<0.01）;100拉德照射后由电镜可见淋巴细胞质膜膨出,细胞核未见异常。更多还原

【Abstract】 This paper reports the functional and structural changesinduced by low dose of ⁶⁰Co γ-Ray on the plasma membrane receptors ofhuman peripheral blood lymphocytes.（1）There was an obvious decrease inthe percentage-of E active rosette forming cells（E_a）after irradiation with 25 rads（P<0.01）,but no futher decrease after irradiation with 100 rads.（2）The percentage of mouse erythrocyte rosette forming cells（Ms）dec-reased significantly after irradiation with 25 rads（P<0.01）and the decrea-ment was more significant at 100 rads.（3）The number of S_mI_gG lymphocy-tes decreased at 25 rads too,there was a significant decrease（P<0.01）since the dosage reached 100 rads.（4）An abnormal protrusion of plasmamembrane was observed under tranmission electron microscope,but no abnor-mality of the nuclei of lymphocytes was observed at 100 rads.Thesefindings suggest that the plasma membrane of lymphoeytes might be one ofthe main sensitive target in irradiation.更多还原