【摘要】 本文报道了八个 DTPA-双(N-烷基酰胺)类化合物的化学合成方法及初步的促排效果。更多还原

【Abstract】 Eight kinds of DTPA-bis（N-alkylamide）compounds were synthesized for removal of incorporated radionuclides,which are chelatingagents and were obtained on condensation of DTPA with eight kinds of N-alkylamines（N-propylamine,N-butylamine,N-amylamine,N-hexylamine,N-heptylamine,N-octylamine,N-nonylamine and N-dodecylamine）,then hydrolysis with NaHCO₃.The hydrolysis products are DTPA-bis（N-alkylamide）.The efficiency of thece Compounds for removal of incorporated ¹⁴⁴Ce and ²³⁴Th on rats has been studied.It was foundthat compounds Pu-2,Pu-3,Pu-4 are more efficient on removal of incorporated radiocerium,and Pu-3 is the most efficient compound.For removal of ²³⁴Th,compounds Pu-3 and Pu-4 are more efficient than the control.更多还原