节点文献

银耳蜜环菌醇提取物的心血管药理研究

STUDY ON EFFECT OF ALCOHOL EXTRACT OF TREMELLA FUCIFORMIS AND ARMILLARIELLA MELLEA (TFAM) ON CARDIOVASCULAR SYSTEM

  • 推荐 CAJ下载
  • PDF下载
  • 不支持迅雷等下载工具,请取消加速工具后下载。

【摘要】 <正> 银耳蜜环菌醇提取物(简称银蜜醇提取物)是银耳和蜜环菌醇提取物的等量混合物。银耳醇提取物是从深层培养的银耳(Tremella fuciformis Berk)(白木耳)中提取,银耳主要含多糖和蛋白质,能强精、补肾、滋阴润肺、补脑及强心等。据研究能提高机体非特异和特异性免疫能力。蜜环菌醇提取物系从固体培养基中培养的蜜环菌[Armillariella mellea

【Abstract】 Alcohol extract of TFAM is a mixture of equal quantities of alcohol extracts of Tramella and Armillariella mellea. It exerts a decrease of heart rate in rats and an inhibitory action on the isolated heart of toads.There is an inhibitory action in the ST segment elevation of myocardial muscles caused by pituitrin in rabbit’s ECG. It can also antagonize ΣST elevation by ligation of the anterior descending branch of coronary artery in anesthetic dogs.A decrease of oxygen consumption and an increase of tolerance to hypoxia induced by isoproterenol in mice are found. An increase in coronary blood flow and decrease of coronary resistance in aneasthetic cats after intravenous injection of drugs are observed.It has a significant inhibitory action on thrombosis in intact rats and it also exerts an significant inhibition of platelate aggregation in vitro.The LD50 of Alcohol extracts of Tramella fuciformic and Armollariella mellea in mice (ⅳ) are found to be 8.6 (7.7—9.5) g/kg.

  • 【下载频次】79
节点文献中: 

本文链接的文献网络图示:

本文的引文网络