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乙型肝炎的传播情况及其与肝癌的关系

The spread of hepatitis B and it’s relation to liver cancer

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【摘要】 本文用敏感的方法检测北京、广西地区不同年龄正常人群和不同肝病患者中之HBsAg、抗-HBs、HBeAg、抗-HBe,发现北京地区以2岁以下组HBsAg阳性率最高(12.4%),抗-HBs随年龄增长而增高。广西地区以4岁以下组HBsAg阳性率最高达21.6%。两者HBsAg阳性中HBeAg阳性率分别为59.2%及77.5%;抗-HBe为11.1%及15.O%。在两地不同慢性肝炎、肝硬化、肝癌患者与HBV感染密切相关,患者组明显高于对照组。孕妇中HBsAg阳性率为6.7%,其中HBeAg阳性为43.2%,用HBIG及乙肝疫苗联合阻断,婴儿全部产生抗-HBs。

【Abstract】 Tests have been made in Beijing and Guangxi on the HBsAg, anti-HBs, HBeAg and anti-HBe among different age groups and patients suffering from chronic liver diseases Results achieved in Beijing showed that the HBsAg positive rate was very high (21.4%) in the under two age-group, while the anti-HBs positive rate increased with age. In Guangxi, the HBsAg positive rate was the highest (21.6%) in the under four age group. Among the HBsAg positive cases, the HBeAg positive rate was 59.2% in Beijing and 77.5% in Guangxi while the antiHBe was 11.1% and 15.0% respectivelyIn both Beijing and Guangxi, the positive cases of HBV were closely related to the incidence of chronic hepatitis, liver cirrhosis and cancer The anti-HBe value for all cases was remarkably higher than that of the control groups.Among pregnant women the pesitive rate was 6.7% for HBsAg and 43.2% for HBeAg Blocking injection of hepatitis B vaccine and HBIG for mother-infant transmission should result in appearance of anti-HBs in all infants.

  • 【文献出处】 北京医学 ,Beijing Medical Journal , 编辑部邮箱 ,1985年04期
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