【摘要】 <正> 猪去氧胆酸（Hyodeoxycholic acid）的结构式见图1,目前是一种降血压药的主要成分,又有可能用于试治胆结石症。它的离解常数（K_a）、活度积常数(K_sp⁰)及临界胶束浓度（CMC）尚未见报道,这些参数对于了解它在胃肠中的吸收等更多还原

【Abstract】 Hyodeoxycholic acid is slightly soluble in water. For determining its Ka and KS0P, it is dissolved in NaOH and then titrated with 4 × 10-3M HCl. Internally electrogene-rated hydroxyl ion instead of reagent NaOH is used, which improve the precision of determination and the rate of titration. The pKa and pKs0p obtained are 5.17-6.12 and 9.07-9.25 respectively, the former increases and the later decreases with the increase of the concentration of sodium hyodeoxycholate titrated.The critical micellar concentration of hyodeoxycholate is determined by surface tension method.更多还原