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乙型肝炎病毒胎内传播的研究

STUDIES OF MATERNAL-FETUS TRANSMISSION OF HEPATITIS B VIRUS

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【作者】 贾希瑜刘崇柏陈吉朝陈梅林

【Author】 Jia Xiyu Liu Chongbai Chen JichaoChen Menlin Hepatitis Department, Institute of Virology, National Centre for Preventive medicine. Epidemic Prevention Station of Zheng Din County, Hebei Province. Pathology Department, The First Affiliated Hospital of Beijing Medical College.

【机构】 中国预防医学中心病毒学研究所河北省卫生防疫站北京医学院第一附属医院病理室

【摘要】 <正> 为了探索HBV胎内感染的可能性及机率,随机配对选取了22例HBsAg携带者母亲的引产胎儿和22例HBsAg阴性母亲的引产胎儿,对其心血、肝脏进行了系统研究,简报如下: 1.对象 随机选择HBsAg阳性无症状带毒者的雷夫奴尔(Rivanol)引产胎儿22例,

【Abstract】 Twenty two autoptic fetal cases from HBsAg positive pregnant women with various gestational ages were studied for HBV congenital infection. Out of the 22 fetal serai samples,one was found to have low titer of HBsAg alone.None of anti-HBcIgM was detectable in all cases .Both HBsAg and HBcAg were found in another 32 week old fetal liver sections by PAP methods,but no HBsAg was detectable in its serum.HBV DNA was also found to be present in the liver frozen sections of this case by in situ hybridization technique.We believe that HBV infection during fetal period in HBsAg positive carrier women is uncommon.

  • 【文献出处】 病毒学报 ,Chinese Journal of Virology , 编辑部邮箱 ,1985年02期
  • 【被引频次】13
  • 【下载频次】27
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