Nine fetus aborted from 9 HBsAg and HBeAg carrier mothers were studied to detect the HBV DNA in hepatocyte genome by Southern blot and hybridization technique utilizing 32p-labelled cloned HBV DNA as a probe. The results showed that HBV DNA was integrated in hepatocyte genome of 3 (No.F27, F31 and F32 ) out of 9 fetus. Among the three, 2 fetus ( F31 apd F32 ) were also positive for HBsAg but negative for HBcAg in hepato- cytes by unlabelled PAP technique ( DAKO PAP Kit) .In the remaining case, the only mark...