【摘要】 唾液酸是一种氨基糖类物质,它与癌的转移、扩散等有关系。据国外报导,癌患者血清中唾液酸含量比正常人的高。 对献血员83人,非癌患者78人,癌患者136人,进行了诊断前测血清唾液酸值。结果:阳性率正常组为20.48％、非癌组为25.65％(P>0.05),说明非癌患者血清中唾液酸的含量与正常人的含量相似。癌的阳性率:胃癌组85％、肝癌组76.67％、肺癌组91.17％、食管癌组87.5％、其他癌组78.57％、肠癌组55.56％,P值均<0.01,所以血清唾液酸数值升高是有价值的诊断依据。 对45例癌患者进行了治疗前后唾液酸测定,其值能帮助临床观察肿瘤的复发和判断预后。更多还原

【Abstract】 Sialic acid is one of the composition of mucopoly saccharides. It is associated with the matastasis and spread of cancer. It is reported that the content of sialic acid in serum of cancer patients is higher than that in normal individuals.In 83 blood donors, 78 patients with noncancerous diseases, and 141 patients with cancers. The level of sialic acid in serum has been determined before diagnosis, when the 70mg% of sialic acid in serum was defined as a positive level, the positive rate of noncancerous group was similar to that of normal individul (20.48%). In cancer patients the positive rate accounts for 85% in gastric cancer group, 76.67% in liver cancer group, 91.17% in lung cancer group, 87.5% in esophageal cancer group, 55.56% in intestinal cancer guoup,78.5% in other kinds of cancer group Thus, according to the elevation of the level of sialic acid in serum a diagnosis of cancer may be made. Sialic acid level in sesum has been determined before and after therapy in 45 Patients with cancer, it has been shown that the change of the level of sialic acid is helpful clinically for the prediction of the relaps of tumor and judging of its prognosis.更多还原