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麦冬及小剂量硫酸镁对急性心肌梗塞后血液动力学、心律失常及心肌梗塞范围影响的实验研究
The Effect of Radix Ophiopogonis and Small Dose MgSO4 on Hemodynamics,Arrhythmia and Extent of Myocardial Infarction in Coronary Occluded Dogs
【摘要】 本文报告麦冬制剂合小剂量硫酸镁对狗实验性急性心肌梗塞的作用,结果表明:麦冬合用小剂量硫酸镁,可预防心肌梗塞后心律失常的发生;降低心肌耗氧量;增加心肌能量供给;限制心肌梗塞范围。值得在临床上进一步观察研究。
【Abstract】 The effect of Radix Ophiopogonis and small dose MgSO4 on hemodynamics,arrhythmia,and extent of myocardial infarction were studied in 18 open-chest anesthetized dogs.The results showed no change of BP but slight increase of EF dp/dt and decrease of HR oxygen consumption.Arrhythmia was found significantly reduced in the treated group than in the control group 6 and 12 hours after infarction.The ultimate infarct extent after 24 hours was significantly reduced in the treated group. It was shown that Radix Ophipogonis combined with small dose of MgSO4 could prevent arrhythmia after myocardial infarction,reduce oxygen consumption and limit the extent of myocardial infarction in experimental animals.
- 【文献出处】 中西医结合杂志 , 编辑部邮箱 ,1984年05期
- 【被引频次】6
- 【下载频次】80