【摘要】 <正> 许多实验研究支持中枢多巴胺(DA),γ-氨基丁酸(GABA)和乙酰胆碱(Ach)参与针刺镇痛过程。多数认为中枢 Ach 是加强针刺镇痛的一个重要环节,但 DA 和 GABA 是拮抗还是协同针效尚难肯定。更多还原

【Abstract】 DA contents in the brainstem and the dience-phalon,and pain threshold in rats were increased byelectroacupuncture.The analgesic effect was partiallyblocked by the i.p.injection of bicueulline(a blo-cker of GABA receptor)or atropine(a blocker ofAch receptor);The increases of DA levels in thebrainstem and the diencephalon caused by electroa-cupuncture analgesia were abolished by the i.p.injection of bicuculline;The increase of DA concen-tration in the diencephalon induced by electroacupu-ncture was reduced,but the DA level in the telen-cephalon was inhanced by the previous injection ofatropine.These results indicate that GABA and Ach systemin brain may play a certain role in electroacupunc-ture analgesia,which may be produced through theDA system in brain.It is also suggested that thereseem to be differential relations between DA andAch in different brain regions in electroacupunctureanalgesic process.更多还原