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78份细胞毒抗血清的HLA-A.B位点特异性鉴定

SPECIFIC DESIGNATION OF HLA-A,B,C LOCUS ANT GENS IN LYMPHOCYTOTOXIC ANTI-SERA

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【摘要】 本文用微量淋巴细胞毒方法鉴定出28份血清,作为分型试剂的使用单价、双价特异性血清。前后已鉴定出作为分型试剂血清共62份,含18种特异性血清,用这些分型试剂检出沈阳地区汉族HLA—A位点抗原的基因频率为0.756,仍有空白0.244,HLA—B位点抗原的基因频率为0.7780,空白0.2220。

【Abstract】 Seventy eight samples of lymphocytotoxic antisra were sercencd from post-partum blood in the vagina after deliver. The microcytotexicity method (used by the international workshop)was adapted in the experiment. The resuls are as follows.Seventy eight lymphocytotoxic anti-sera wr designated to 26 sra as typing reagent contaiing mono or dual op. rational specific sra. Sice 1930 the authors have designated 58 sera as typing reagent, contaiing 18 kinds of specific sera. Using these typing reagents, HLA-A Lceus antigen g ne frquency of Han nation in Shenyang ara was found to be 0.726, with the blank 0.244, HLA-B Locus antigen gene frquerey 0.778, with the blank 0.222.

  • 【文献出处】 中国医科大学学报 ,Journal of China Medical University , 编辑部邮箱 ,1984年05期
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