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HLA系统在汉、蒙、朝鲜三个民族间相关性的研究

THE RELATIONSHIP OF THREE ETHNIC GROUPS (THE HAN NATION,THE MONGOLIAN NATION AND THE KOREAN NATION) BASED ON THE HLA SYSTEM

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【作者】 宋芳吉苏霄汉李惠刚徐沈育刘子勇陈洪铎顾绍裘薛哲明

【Author】 Song Fangji et al Dept of Dermatology and Immunology Lab First Affiliated Hospital

【机构】 中国医科大学附属第一医院临床免疫研究室阜新蒙古族自治县人民医院

【摘要】 本文对汉、蒙、朝鲜三个民族的HLA系统抗原频率进行了比较。结果:汉、蒙族间HLA—A2,HLA—A28,HLA—B5,HLA—Cw2、HLA—Cw4蒙族略低于汉族;汉、朝鲜族间HLA—A9,HLA—B15、HLA—B5、HLA—Bw22朝鲜族明显高于汉族;蒙、朝鲜族间HLA—B5、HLA—B15,HLA—Bw22朝鲜族明显高于蒙族。经遗传距离计算,初步见到三个民族的亲缘关系非常密切,

【Abstract】 This survey covers 105 persons of unrelated Han nation (aging 21 to 56, 56males 49females), 104 of unrelated Mongolian nation (aging 16-18, 55males 49 females) and 100 of unrelated Korean nation (aging 18~58, 32males 68 females). Antigens freguency in HLA system was compared among the Han, the Mongolian and the Korean nations with the method of the microcytotoxicity (the method used in international workshop), in which HLA typing sera were supplied by the American Red Cross and were typed by our own laboratoryThe result obtained was as follows. HLA-A2, HLA-A28, HLA-B5, HLA-CW2 and HLA-CW4 in Mongolian persons are slightly lower those in Han persons. HLA-A9, HLA-B15 and HLA-BW22 in Korean persons are Obviously higher than those in Han person. HLA-B5, HLA-B15 and HLA-BW22 In Korean persons are obviously higher than those in Mongolian persons. According to the calculated genetic distance of these three nations it was preliminarily found that the relationship of these three nations is very close Each haplotypc having significant linkage diseguilibrium is not uniform among three nations.

  • 【文献出处】 中国医科大学学报 ,Journal of China Medical University , 编辑部邮箱 ,1984年05期
  • 【被引频次】1
  • 【下载频次】25
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