【摘要】 <正> 磷酸肌酸激酶(CPK)是一种器官特异的酶,以骨骼肌含量最为丰富,心、脑次之,其余器官含量甚微,红细胞不含此酶。当心肌坏死、损伤或细胞膜通透性增大时,位于胞浆中的 CPK 渗漏出细胞,所以血清中 CPK(SCPK)升高,以此应用于临床心血管疾病的诊断。更多还原

【Abstract】 1.Utilizing the method of creatine determination,this test determined serum pho-sphocreatine kinase of 64 childrens with Keshan disease and 44 as contrast in Yun-nan Province.The SCPK activity of patients of acute type,subacute type,chronictype was higher than contrast.It was statistically significant.Between the patientsof restoration period and contrast children’s SCPK activity there was no differen-ce.the continuous change of patient’s SCPK activity closely related to the patient’scondition.whether getting better or worse.So that the determination of SCPK activ- ity may provide not only objective basis for early diagnosis,but also the objectiveindex for prognosis of Keshan disease.2.When we treated patient of Keshan disease with ragitin intravenous drip,electrocardiogram had transient change before or after treatment,but SCPK activitywas unchanged.The result showed that it is a safe,applicable and theraputic methodof diagnosis with argitin intravenous drip when used in early stage of Keshan dise-ase.更多还原