【摘要】 本文通过在地方性氟中毒地区居民及氟骨症患者的尿氟排泄水平,试图评价尿氟在地方性氟中毒临床诊断及防治中的意义。 调查结果可见,地方性氟中毒病区居民其尿氟含量与饮水含氟量及饮水中氟的含量增高有密切的关联,呈正相关趋向。在高氟饮水地区居住的非氟骨症人群及氟骨症患者间,其尿氟含量也与饮水含氟量呈正相关,但两组人群尿氟排出量未见显著性差异。地方性氟中毒患者其发病程度与尿氟排出量高低亦无规律可循,个别病例却呈交叉现象。 结果表明,尿氟排出量作为接触氟强度和机体负荷状态的监测指标是适宜的,作为地方性氟中毒临床诊断或防治的观测指标或依据是不适宜的。更多还原

【Abstract】 In order to find out a parameter for the medical diagnosis and therapeutic criteria of endemic fluorosis, the excretory level of fluorine in urine was determined between the patients of bone fluorosclerosis and those who lived in the district of endemic fluorosis. The results showed that both the patients and the normal people in the endemic area of fluorosis excreted more fluorine in urine than the others, because of drinking highly fluorina-ted water. Thus a positive correlation was found between the amount of fluorine in urine and the degree of fluorinated drinking water, while no significant difference was found between the patients and the normal individuals. The urinary output of fluorine fluctuated in a few cases of fluorosclerosis.From the data obtained we may, perhaps, conclude that the excretion rate of fluorine in urine may be considered as a parameter of fluorine overload in the body, but not as applicable to the medical diagnosis or treatment in fluorosis.更多还原