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测定脐血清促甲状腺激素水平筛选新生儿先天性甲状腺功能低下
Screening Survey of Neonatal Congenital Hypothyroidism by Umbilical Serum TSH Determination
【摘要】 <正> 先天性甲低的患病率约1/5,000~1/10,000,可以危害新生儿多种代谢和生长发育,特别是中枢神经系统损伤。可造成新生儿不可逆性智力低下。如果在生后3个月
【Abstract】 Because of the irreversible mental retardation of congenital hypothyroidism can be prevented by early treatment, the importance of early diagnosis of this disease has been emphasized.We choose the method of measuring serum TSH for screening neonatal hypothyroidism by cord blood. As an initial screening test, it has a higher specificity for the diagnosis of primary hypothyroidism and the blood sample is easy to obtain. Excess serum is also readily available for repeated analyses.Cord serum TSH was determined in 8018 infants. The distribution of the values is skew. The median value was 7.7 μIU/ml. The incidence of neonatal hypothyroidism was 1/8018 in our investigation.
- 【文献出处】 天津医药 ,Tianjin Medical Journal , 编辑部邮箱 ,1984年11期
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