【摘要】 <正> 原发性高血压的发病过程和肾素—血管紧张素系统关系密切。为寻找发病因素,我们曾就本病患者血浆肾素活性(PRA)和血管紧张素Ⅱ(ATⅡ)对流行病学一些因素的关系作单因素关系分析,使用的方法为均值更多还原

【Abstract】 By using multiple regression analysis a series of clinical data concerning plasma renin activity (PRA) and angiotensin Ⅱ(ATII) level of 218 patients with untreated essential hypertension were studied. All the patients had an unrestricted salt intake, and were divided into three groups just based on the differences of profession (physical or mental work) and the postures during blood sampling (in sitting or supine position). The data obtained from these three groups showed that PRA and ATII were significantly correlated. PRA and ATII were closely correlated with ECG changes and professional differences. Some other correlations were positive family history versus PRA; complications, systolic pressure and diastolic pressure versus ATII. Neither PRAnor ATII had significant correlation with sex. age, course of the disease, smoking, body built. cardiac otttput, cardiac index and total peripheral resistence. All the selected factors relating to PRA or ATII in all groups had found a suitable multipleregression equation which could be used as a referential guide for conducting the prophylactic and therapeutic work thereafter.更多还原