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子宫颈癌前病变和早期癌细胞、病理学的对照研究

Comparative Cytological and Pathologic Studies of Precancerous Lesion and Early Cancer of Cervix Uteri

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【摘要】 <正> 近年来,随着细胞学诊断的进步,应用细胞学诊断宫颈癌前病变和早期癌,已不止单纯采用巴氏分类法,而是综合分析细胞涂片,借以推测其病理组织改变。同时由于广泛开展细胞学普查,宫颈癌前病变和早期癌

【Abstract】 From 1972 to 1979, 224 cases of uterine cervical lesions were collected and analyzed, including 38 cases of severe dysplasia, 162 cases of carcinoma in situ (CIS), 24 cases of early invasive carcinoma and 100 cases of invasive squamous cell carcinoma of cervix. Operations were performed on 8 cases of severe dysplasia, 37 cases of CIS and 24 cases of early invasive carcinoma. Wertheim’s operation, total hysterectomy or cone excision was employed.Cytological studies including cell pattern, such as: (isolated or in clumps, nuclear shape, nuclear chromatin pattern, nuclear area, N/C ratio) and histopathological studies including cell differentiation and depth and extent of invasion of lesion were performed.The number of atypical cells increases whenever the ring extention is bigger than 2/4 and longitudinal extention is bigger than 7mm. Cytological appearance of dysplasia and CIS are different. Cells of former are usually isolated, nuclear chromatin is evenly fine and N/C ratio is lower than CIS. CIS and early invasive carcinoma are also different. Early invasive carcinoma, as seen in cytological smears, showes large cell clumps with coarse chromatin granulars, and increases the number of keratinized cancer cells and large nucleolus. When early invasive carcinoma and invasive carcinoma are compared, the latter has bizarre malignant cells and tumor diathesis. Certainly in some cases the distinction is difficult to make. However, cytological studies will be of some value for clinical reference.

  • 【文献出处】 天津医药 ,Tianjin Medical Journal , 编辑部邮箱 ,1984年01期
  • 【被引频次】1
  • 【下载频次】10
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